South Carolina runs from Greenville and the Upstate through the Midlands to Charleston, Myrtle Beach and the rest of the coast, with major medical centers in Greenville, Spartanburg, Columbia, Florence and Charleston. EnviCare serves South Carolina statewide. We're a large regional Southeast medical waste company headquartered at our CareCenter in Cartersville, Georgia, with a local CareExchange in Columbia. Our fleet runs from route trucks to tractor trailers, sized for anything from a single dental office to a hospital system or a full records cleanout.
Call 888-697-6342 or request a quote for South Carolina medical waste pickup.
Medical Waste Services in South Carolina
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Regulated medical waste pickup - Red-bag biohazardous waste, microbiological waste, blood and blood products, pathological waste and contaminated animal waste, picked up on a schedule that fits your volume.
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Sharps disposal - Our reusable sharps container program, or disposable sharps containers in several sizes, which you can also order through the EnviCare shop.
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Pharmaceutical waste disposal - Pickup and destruction of non-hazardous pharmaceuticals, plus pharmaceutical mail-back kits for controlled and non-controlled medications. Kits return to our Cartersville facility for documented destruction.
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Trace chemotherapy waste - Yellow containers for the empty vials, IV bags, tubing, gloves and gowns left from chemo prep and administration.
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NAID AAA certified document destruction - Off-site paper shredding with a certificate of destruction for every job, plus large-volume paper purges and cleanouts.
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Secure document storage - Secure storage for paper records, available across all the states we serve.
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Documented hard drive destruction - Hard drives and other data-bearing devices are physically destroyed and documented with a certificate of destruction.
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E-waste recycling - Pickup anywhere in South Carolina, or drop-off at our Cartersville plant, for retired computers, monitors, printers and other IT equipment.
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OSHA and HIPAA compliance training - Bloodborne Pathogens, Hazard Communication and HIPAA training, with written plans and training records in one place. Includes DOT medical waste training, which federal rules (49 CFR 172.704) require for employees who sign medical waste manifests.
Who We Serve in South Carolina
Our South Carolina clients include:
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Hospitals, surgery centers and infusion centers - higher-volume regulated waste, trace chemo, reusable sharps and pharmaceutical waste.
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Physician, specialty and urgent care practices - single offices and multi-site groups.
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Dental offices and oral surgeons
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Veterinary clinics and animal hospitals
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Research, university and clinical labs
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Dialysis centers and blood banks
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Nursing homes, assisted living facilities, home health and hospice agencies
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Pharmacies - independent, chain and long-term care pharmacies.
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Funeral homes and tattoo studios
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Records-heavy offices - practices closing, merging or clearing storage.
South Carolina Medical Waste Compliance
South Carolina calls medical waste infectious waste and regulates it under the South Carolina Infectious Waste Management Act (S.C. Code § 44-93-10 et seq.) and Regulation 61-105, last amended May 23, 2025. The program is run by the South Carolina Department of Environmental Services (SCDES), Bureau of Land and Waste Management. SCDES took over the environmental programs of the former SC DHEC on July 1, 2024.
Here's what the rules mean for a typical South Carolina facility:
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Register as a generator. Every in-state generator must register with SCDES, each site separately, and renew every three years (R.61-105 Section F). Annual fees depend on monthly volume: none under 50 pounds, $150 for 50 to 999 pounds, and $600 for 1,000 pounds or more.
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Small quantity generators. Facilities producing less than 50 pounds a month still register and must manage sharps, cultures, and blood and blood products under the rules (Section G).
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Packaging and labels. Sharps go in rigid, leak-resistant, puncture-resistant containers, and inner bags must be red or orange (Section I). Each outer container needs the biohazard symbol, your SCDES generator number, and the date it went into storage or was shipped (Section J).
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Storage limits. Generators may store infectious waste on site for no more than 14 days, or 30 days if kept at or below 42°F (Section K).
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Manifests. Every off-site shipment must travel with a manifest on SCDES Form 2116 or another SCDES-approved form, signed by the generator, and the generator keeps a copy (Section M).
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Registered transporters. Transporters must register with SCDES every year and put their SCDES transporter number on each manifest (Sections N and O).
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Hazardous pharmaceuticals. South Carolina has adopted EPA's hazardous waste pharmaceuticals rule (R.61-79.266 Subpart P), including the ban on flushing them down the drain.
EnviCare is a registered South Carolina infectious waste transporter (SCDES registration IWT000008) and appears on SCDES's published list of infectious waste transporters. All South Carolina waste is treated at EnviCare's permitted treatment facility in Georgia, which South Carolina allows as an out-of-state destination facility. Every pickup comes with an SCDES-approved electronic manifest that carries all the Section M fields and generator certifications, so it meets South Carolina's manifest rule (R.61-105 Section M).
OSHA and HIPAA Training and Plans
On top of state rules, inspectors usually ask for four documents first. EnviCare's compliance platform covers HIPAA risk analysis and policies, OSHA Bloodborne Pathogens training and an Exposure Control Plan, OSHA Hazard Communication training and a written plan, and a medical waste plan, all tracked in one dashboard.
This section is a summary, not legal advice. Confirm your facility's obligations with SCDES.
How Medical Waste Pickup Works
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Call or request a quote. Tell our Client Care Team what you generate, how much, and where.
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Get the right containers. We set you up with biohazard boxes or reusable containers, reusable or disposable sharps containers, pharmaceutical and trace-chemo containers, and shredding bins as needed.
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Choose your schedule. Weekly, every other week, monthly or on call, set to your volume and South Carolina's storage limits.
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We pick up and document. Our drivers collect your sealed containers, and you get an electronic manifest after every pickup. High-volume sites and large cleanouts get tractor-trailer capacity.
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Treatment and records. All South Carolina waste goes to our permitted treatment facility in Georgia, and your manifests and certificates of destruction are available whenever you need them.
South Carolina Cities We Serve
EnviCare serves South Carolina statewide, from Greenville and the Upstate to Charleston and Myrtle Beach, including:
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Upstate - Greenville, Spartanburg, Anderson, Greer, Simpsonville, Easley, Clemson and Gaffney
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Charlotte region - Rock Hill, Fort Mill and Lancaster
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Midlands - Columbia, Lexington, Irmo, Sumter, Orangeburg, Newberry and Camden
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Aiken area - Aiken and North Augusta
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Pee Dee - Florence, Darlington and Hartsville
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Grand Strand - Myrtle Beach, Conway and North Myrtle Beach
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Lowcountry - Charleston, North Charleston, Mount Pleasant, Summerville, Goose Creek, Beaufort, Bluffton and Hilton Head Island
South Carolina Medical Waste FAQ
Do you serve all of South Carolina?
Yes. EnviCare serves South Carolina statewide, from Greenville and Spartanburg through Columbia and Florence to Charleston, Myrtle Beach and Hilton Head. We also have a local CareExchange in Columbia.
Who regulates medical waste in South Carolina?
The South Carolina Department of Environmental Services (SCDES) regulates infectious waste under the Infectious Waste Management Act and Regulation 61-105. SCDES took over this program from SC DHEC in July 2024. OSHA and the U.S. Department of Transportation also have requirements.
Does South Carolina require medical waste transporters to be registered?
Yes. Infectious waste transporters must register with SCDES every year and receive an SCDES transporter number, which must appear on every manifest. EnviCare holds SCDES registration IWT000008 and is on SCDES's published transporter list.
Do South Carolina generators need a manifest?
Yes. Every off-site shipment needs a manifest on SCDES Form 2116 or another SCDES-approved form, and the generator keeps a copy. EnviCare's electronic manifest for every pickup is SCDES-approved and meets South Carolina's manifest rule (R.61-105 Section M).
How long can we store infectious waste before pickup?
No more than 14 days on site, or 30 days if kept at or below 42°F. We set your pickup schedule to stay inside those limits.
We have locations in Georgia or North Carolina too. Can one company handle all of them?
Yes. EnviCare serves South Carolina, Georgia, Alabama, Mississippi, Tennessee, North Carolina and Louisiana statewide, plus North Florida, so multi-state groups can use one provider.
Schedule Medical Waste Pickup in South Carolina
Get dependable pickup and one point of contact from Greenville to Charleston. Call EnviCare at 888-697-6342, email care@envicare.net, or request a quote online.
Also serving: Georgia · Mississippi · North Florida · North Carolina · Tennessee · Alabama · Louisiana
